Odontogenic tumors are heterogeneous group of lesions with diverse histopathological and clinical features. Ameloblastic fibro-dentinoma. The ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumor. .. It is also distinguishable from ameloblastic fibro-dentinoma not only because it. Peripheral ameloblastic fibro-dentinoma (AFD) is an extremely rare benign mixed odontogenic tumor. From a review of the English-language literature, to the.

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OPG showed unerupted tooth bud of upper right second molar and was being prevented from eruption by the odontome.

Aggressive atypical ameloblastic fibrodentinoma: Report of a case

Indexed in Web of Science. A fibrillar pattern reminiscent of dentinal tubules was noted in the focal area as marked [ Figure 4 ].

The first is a neoplastic lesion, which if left in situ does not appear to mature further. The peripheral types of mixed odontogenic tumors are much rarer than their intraosseous counterparts [ 1 — 6 ].

Aggressive atypical ameloblastic fibrodentinoma: Report of a case

World Health Organization classification of tumours; pp. Under general anaesthesia, the lesion was enucleated and the permanent right upper dentknoma molar tooth bud removed. Oral panoramic radiograph showed a radiopaque mass with a radiolucent border in the right posterior maxilla covering almost the whole right maxillary tuberosity Fig.

Report of two cases. A Rarity in Ameloblasitc Tumors. Minute calcifications were evident within the lesion [ Figure 3 ]. Orthopantamograph revealed a well defined unilocular radiolucency fbro from 72 to 85 Click here to view. Immediately after the eruption, it was positioned more palatally than the adjacent incisors. Dentinoma has been defined as a very rare odontogenic neoplasm composed of odontogenic epithelium and immature connective tissue and characterized by the formation of dysplastic dentin.

Open in a separate window. The patient is kept under regular follow-up in order to rule out any recurrence. The treatment plan was approved in the joint discussion by the maxillofacail surgeons, pedodontist and oral pathologist who are co authors for this paper.


Most studies suggest that conservative excision of the tumor with minimal but adequate margins is the treatment of choice [ 46 ]. Support Center Support Center.

The age of our patients provides further evidence that contradicts this conclusion as our patient is an extremely young child. Our initial but tentative diagnosis was a pyogenic granuloma. Occasionally, it may be associated with unerupted tooth. AFO is amelob,astic found in young patients, with no significant ameloblasric predilection. Considerably more information on the AFD has to be collected in order to better understand the lesion, its biological behavior, risk of malignant transformation and relationship to the other AF-related lesion.

Owing to the formation of dentine, whether a primitive osteodentin or the very rare mature tubular type of dentine, the tumor appears as a mixed radioopaque and radiolucent lesion with well-defined borders. Although the mechanism of malignant transformation of AF and other related benign mixed odontogenic tumors remain unsettled, multiple surgical procedures of recurrent lesions remain one of the important factors in their malignant transformation. The dentinpma extraosseous tumors do not appear in the oral mucosa other than gingiva.

Histopathology On gross examination the specimen consisted of a hard tissue mass with a soft tissue attachment. The age range is 2. Ameloblastic fibro-odontosarcoma of the mandible: This case report amelobblastic the surgical treatment of an odontogenic tumour in the maxilla.

Considering the clinical and radiological picture the possible differential diagnosis was calcifying edntinoma odontogenic tumour CEOTadenomatoid odontogenic tumour AOT and ameloblastic fibro-odontoma. J Bangaladesh Coll Phys Surg. The slides were counterstained with Mayer hematoxylin and photographed using an optical microscope BX61; Olympus, Tokyo, Japan equipped with an imaging system Stream; Olympus.

A case presentation and histological comparison with ameloblastic fibrodentinoma. Clinical and radiographic appearances. J Oral Pathol ; Sporadic recurrences of AFO have been attributed to the inadequate surgical removal at fobro time of initial treatment.


Periodontol ;57 1: Ameloblastic fibrodentinoma, ameloblastic fibroma, odontogenic tumor. Some of the stromal cells, leukocytes, and endothelial cells were also positive for CD44 staining. Author information Article notes Copyright and License information Disclaimer.

Common signs and symptoms of AFO are asymptomatic swelling, delayed tooth eruption in the affected region and a well-defined mixed radiological appearance that is similar to dntinoma odontogenic neoplastic formations, such as immature complex odontoma, calcifying epithelial odontogenic tumour and adenomatoid odontogenic tumour.

Khalam were the surgeons, Dr. Introduction The ameloblastic fibro-odontoma AFO is a rare benign odontogenic lesion defined as a tumour with the general features of ameloblastic fibroma but that also contains enamel and dentine. How to cite this article: The age range is 12—83 years, with a peak in the third decade.

Ameloblastic fibro-odontoma

Abstract Ameloblastic fibroma and related lesions constitute a group of lesions, which range in ddentinoma behaviour from true neoplasms to hamartomas. Based on the existing literature, amelogenin secreted by the odontogenic epithelium may contribute to the red appearance of the lesion. In some of the cases previously diagnosed as AFD, dentine matrix or dentinoid tissue is an area of hyalinization around the epithelial component, and some workers have dentino,a that hyalinized material may not represent dentine formation.

A one-year postoperative follow-up revealed no evidence of recurrence, but only a mild gingival inflammation Figure 3. The lesion was enucleated out with relative ease.

First, a gingival lesion is subject more than its intraosseous counterpart to constant irritation from plaque, calculus, food impaction, and low-grade trauma.

The calcified matrix in the tissue sections was also positive for amelogenin staining. Ameloblastic fibrodentinoma involving anterior maxilla:

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