Antidysrhythmic agents, which are also known as antiarrhythmic agents, are a broad category of medications that help ameliorate the spectrum of cardiac. The ultimate goal of antiarrhythmic drug therapy is to restore normal rhythm and conduction. When it is not possible to revert to normal sinus rhythm, drugs may. Antidysrhythmic Drugs: Amiodarone, Digoxin, Disopyramide, Flecainide, Lidocaine, Procainamide, Quinidine answers are found in the Davis’s Lab & Diagnostic.

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They decrease conduction through the AV node. Other types of antiarrhythmic drugs affect the duration of action potentials, and especially the effective refractory period.

antidysrrhythmic The problem arises from the fact that many of the antiarrhythmic agents have multiple modes of action, making any classification imprecise. Antiarrhythmic agents Cardiac electrophysiology.

CV Pharmacology | Antiarrhythmic Drugs

By using antidysrhythmlc site, you agree to the Terms of Use and Privacy Policy. Used in supraventricular arrhythmias, especially in heart failure with atrial fibrillation, contraindicated in ventricular arrhythmias.

Classes of drugs used in the treatment of arrhythmias are given below. Quinidine Ajmaline Procainamide Disopyramide.

Antiarrhythmic agent

Mechanism of Action Antidysrhythmic drugs work by correcting abnormal cardiac function. Accessed December 31, Class I drugs work on sodium channels, and are subdivided in a, b, and c classes. Cardiovascular Pharmacology Concepts Richard E. The new scheme will additionally aid development of antiddysrhythmic drugs under development and is illustrated below. Class III agents predominantly block the potassium channelsthereby prolonging repolarization.


Decreasing conduction velocity can help to abolish tachyarrhythmias caused by reentry circuits.

Abnormal automaticity is thought to occur due to reduced resting membrane potential, causing the membrane to be closer to the threshold for generating an action potential. To find out more, including how to control cookies, see here: Class IV agents are slow non-dihydropyridine calcium channel blockers. You are commenting using your Twitter account. Antiarrhythmic agentsalso known as cardiac dysrhythmia medicationsare a group of pharmaceuticals that are used to suppress abnormal angidysrhythmic of the heart cardiac arrhythmiassuch as atrial fibrillationatrial flutterventricular rdugsand ventricular fibrillation.

Otherwise antieysrhythmic is hidden from view. It starts by considering the range of pharmacological targets, and tracks these to their particular cellular electrophysiological effects.

Antiarrhythmic agent – Wikipedia

Leave a Reply Cancel reply Enter antidysrnythmic comment here The ‘stabilizing’ word is used to describe the decrease of excitogenicity of the plasma membrane which is brought about by these agents.

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Retrieved from ” https: Antidotes Contrast media Radiopharmaceuticals Dressings Senotherapeutics. Class I agents are divided into three antidysdhythmic Ia, Ib, and Ic based upon their effect on the length of the action potential. Decongestants Bronchodilators Cough medicines H 1 antagonists.

Antiarrhythmic Drugs

The class III agents exhibit reverse-use dependence their potency increases with slower heart rates, and therefore improves maintenance of sinus rhythm. Prevents paroxysmal atrial fibrillation Treats recurrent tachyarrhythmias of abnormal conduction system Contraindicated immediately after myocardial infarction. Include known drug allergies, as well as second or third-degree AV block, a bundle branch block, cardiogenic shock, sick sinus syndrome, and other major ECG changes.

Class I agents are called membrane-stabilizing agents. Class I agents block the rapid inward sodium channel, slow the rate of rise of phase 0, and so decrease the rate of depolarization. From Wikipedia, the free encyclopedia. All antiarrhythmic drugs directly or indirectly alter membrane ion conductances, which in turn alters the physical characteristics of drugx action potentials. Those proposed in were:

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