Med Mycol. Nov;51(8) doi: / Epub Jul Invasive infections due to Candida norvegensis and Candida. Abstract. Candida inconspicua and Candida norvegensis are two closely related species rarely involved in invasive infections. The purpose of this study was to. PDF | Candida norvegensis has been an unusual cause of infections in humans. In Norway this species was isolated from eight patients from.

Author: Balrajas Darisar
Country: Reunion
Language: English (Spanish)
Genre: Travel
Published (Last): 21 June 2016
Pages: 406
PDF File Size: 20.87 Mb
ePub File Size: 6.3 Mb
ISBN: 676-5-42422-149-3
Downloads: 13216
Price: Free* [*Free Regsitration Required]
Uploader: Dukus

As broad-spectrum antibiotic therapy was administered, prophylactic fluconazole was maintained during outpatient antibiotic treatment.

Case report and literature review ‘ Infectious Disease Reportsvol. The prevalence and clinical significance of microcolonies when tested according to contemporary interpretive breakpoints for fluconazole against Candida species using E-test.

In the case we report, the patient received fluconazole as prophylaxis due to the multiple history of abdominal surgery, the need for a central venous catheter, and the use of broad spectrum antibiotics during a long period of time, all of them being risk factors for the development of candidemia.

The patient was discharged on a standard immunosuppressive regimen with tacrolimus 3 mg every 12 hoursmycofenolate mofetil mg every 12 hours and prednisone 5 mg every 12 hours.

Antifungal susceptibility of Candida norvegensis and Candida inconspicua strains as etiologic agent of fungemia. Clin Microbiol Dandida, 18pp. According to the drug, the following reading criteria were norvegenwis to define the minimal inhibitory concentrations MICs: In previous reports, mortality among patients with IC due to C. The microbiological tests collected on day 1 yielded C. Altogether, samples and samples patients were found positive for C. In our patient, the in vitro susceptibility of C.


Candida norvegensis fungemia in a liver transplant recipient | Revista Iberoamericana de MicologĂ­a

Related articles in Web of Science Google Scholar. The incidence of candidemia due to non- Candida albicans Candida species has been progressively increasing in recent years. Google Wikimedia Wikipedia Wikispecies. Conflict of interest Nothing to declare.

Scand J Infect Dis. Obligate or homotypic synonyms: It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide.

Candida norvegensis: a fluconazole-resistant species.

The use of fluconazole as antifungal prophylaxis has been described as a risk factor for the development of infections by fluconazole resistant Candida strains. Skip to search form Skip to main content.

Candida is an increasing cause of bloodstream infections, being the fourth microorganism to be isolated frequently in blood cultures in the United States 29 acndida the seventh cause of nosocomial infection in our center. Restriction enzyme analysis of ribosomal DNA shows that Candida inconspicua clinical isolates can be misidentified as Candida norvegensis with traditional diagnostic procedures.

Surgery and effective antifungal therapy seem to be together essential for a favorable outcome in patients with intrabdominal abscesses, as observed in our patient and in those reported in literature.


In the following days, the clinical conditions of the patient improved with resolution of fever, achievement of hemodynamic stability and weaning from MV. Because of the primary graft dysfunction, the patient received a third liver transplantation 7 days later.

PappasCarol A.

Candida norvegensis fungemia in a liver transplant recipient.

Epidemiology and outcomes of candidemia in patients: Fungal infections in solid organ transplantation. Fluconazole prophylaxis of severe Candida infection in trauma and postsurgical patients: After one month of hospital stay, the patient was discharged on good health conditions nogvegensis he remained asymptomatic during one year of follow-up.

Despite intravenous antibiotics, the patient’s general condition worsened. Epidemiology and outcomes of candidemia norvetensis patients: Our results and those from the ARTEMIS study underline the lack of cross-resistance between azole derivatives, most recent dugs such as posaconazole and voriconazole exhibiting high efficacy against both species.

Please review our privacy policy. After two weeks from discharge he was readmitted for fever, malaise and moderate hepatic dysfunction.

Author: admin