Erythema multiforme is divided into major and minor forms and is now regarded as distinct from Stevens–Johnson syndrome (SJS) and toxic epidermal. dermal necrolysis, where erythema multiforme minor is the mildest type .. Gavaldá-Esteve C, Murillo-Cortés J, Poveda-Roda R. Eritema multiforme. Revisión y. Find out about erythema multiforme, a skin reaction that usually causes a rash for a few weeks.

Author: Zurr Zulkishicage
Country: Dominica
Language: English (Spanish)
Genre: Travel
Published (Last): 15 May 2008
Pages: 169
PDF File Size: 15.26 Mb
ePub File Size: 15.11 Mb
ISBN: 463-4-22648-773-6
Downloads: 70278
Price: Free* [*Free Regsitration Required]
Uploader: Saramar

Search other sites for ‘Erythema Multiforme’. Updated by Dr Delwyn Dyall-Smith, Call your provider right away if you have symptoms of EM.

Search other sites for ‘Erythema Multiforme Major’. Disease or Syndrome T Erythema annulare centrifugum Erythema marginatum Erythema migrans Erythema gyratum repens. Pathophysiology Severe clinical variant of Erythema Multiforme Previously thought to be part of same spectrum as Erythema Multiforme Minor Now thought to be clinically distinct.

Whether this is a limited form of erythema multiforme has not been determined. Besides the skin sores and mouth sores, there may be sores in the eyes, genitals, lung airways, or gut. It is also multiformme as Fuchs syndromeand mucosal erythema multiforme may occasionally be due to recurrent herpes simplex.

Erythema multiforme

Complications of EM may include: Diseases of the skin and appendages by morphology. Irritation or even pressure from clothing will cause the erythema sore to continue to expand along its margins for weeks or months, long after the original sore at the center heals.


Br J Oral Maxillofac Surg. The blotches develop over a few days into round target often called “bulls-eye” shapes with red, pink, and pale rings.

People with EM often have family members who have had EM as well. EM usually goes away on its own with or without treatment. Erythema multiforme due to Mycoplasma pneumoniae infection in two children. Corticosteroids inhibit lymphocyte binding eritemw endothelium and intercellular adhesion: These images are a random sampling from a Bing search on the term “Erythema Multiforme Major.

Content is updated monthly with systematic literature reviews and conferences. Your health care provider will look at your skin to diagnose EM.

Labs No lab tests are specific for Stevens Johnson Syndrome. Symptoms of EM include: Response to treatment with systemic corticosteroids.

Erythema multiforme in children

EM is a type of allergic reaction. Necrolytic migratory erythema Erythema toxicum Erythroderma Palmar erythema Generalized erythema. Erythema multiforme EM Erythema multiforme minor of the hands note the blanching centers of the lesion Specialty Dermatology Erythema multiforme EM is a skin condition of unknown cause; it is a type of erythema possibly mediated by deposition of immune complexes mostly IgM -bound complexes in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure.

When should these children receive steroids, and when should the illness be allowed to follow its natural course without steroid treatment? Occasionally, doctors won’t know what caused the rash to develop, but still can help someone heal.


This is believed to be nearly always due to HSV-1 infection.

Erythema Multiforme

In most cases, it occurs in response to an infection. Lesions usually evolve over 72 hours. Infections that may lead to EM include: The lesions may appear anywhere in the body but they occur more commonly in the palms, soles, dorsum of the hands, and extensor surfaces.

Do you have questions about the effects of drugs, chemicals, radiation, or infections in children?

Erythema multiforme in children

Many drugs have been reported to trigger erythema multiforme, including barbiturates, non-steroidal anti- inflammatory drugspenicillinssulphonamides, phenothiazines and anticonvulsants. Prevention Patient Education when prescribing drugs associated with Stevens-Johnson Immediately stop suspected drug see causes above if symptoms suggestive of Stevens-Johnson Skin pain, redness or Blister development with systemic symptoms e.

If someone you know has it, it can’t be passed to you. Significant eye involvement in erythema multiforme major may rarely result in serious problems, including blindness. Mucosal lesions, if present, typically develop a few days after the skin rash begins.

Author: admin