This article reviews potential anti-dengue activities from plants distributed . In the Philippines, Euphorbia hirta, known locally as “tawa–tawa”. Management of thrombocytopenia and flu-like symptoms in dengue patients with herbal water of Euphorbia hirta. Mir M, Khurshid R, Aftab R. BACKGROUND. PDF | Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue.
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View at Google Scholar E.
Ocimum sanctum Ocimum sanctum belongs to family Labiatae. A low dose of Q. There are reports on medicinal plants extracts and essential oils possessing potential to new antiviral properties [ 4142 ].
The inhibitory properties against DENV-2 of the sulfated polysaccharide from Gymnogongrus griffithsiaekappa carrageenan 5 was evaluated in Vero cells [ 60 ]. This article has been cited by other articles in PMC.
To overly validate the traditional claim, more studies on contemporary pharmacological approaches including isolation of active compounds and elucidating the mode of action of antidengue activities are warranted. Introduction Etiology of dengue fever Dengue fever is caused by the arthropode-borne flavivirus named dengue virus DENVtransmitted by the Aedes aegypti mosquito [ 1 ]. Degnue is a brown seaweed found naturally in Okinawa, Japan. It is transmitted to humans by Aedes mosquitoes, mainly Aedes aegyptian urban breeding mosquito [ 1 ].
Topical dosage forms i. At this point, the virus in the cell fluid starts to reproduce. The methanolic extract of M.
Potential anti-dengue medicinal plants: a review
Studies on the development of tetravalent vaccines are ongoing in Thailand and these should be available in the near future [ 6 ]. The investigators concluded that E hirta was deemed important by the three indigenous communities as treatment for the symptoms, thus, further investigation is necessary to prove the efficacy and safety of E hirta for dengue fever.
Aspirin should be avoided because it may cause bleeding [ 9 ]. Quercus lusitanica Quercus lusitanica belongs to family Fagaceae. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, degnue, and reproduction in any medium, provided the original author s and the source are credited.
View at Google Scholar S. Similarly, the decrease in hematocrit values was not significant.
Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence
Particularly for dengue, a commercial formulation capsule has been developed and the local communities in the Philippines hitta it as a treatment for dengue [ 17 ].
If pursued from drugs derived from medicinal plants around the continents, this work may prove valuable to the health of individuals and to nations.
The symptoms of dengue range from a mild flu-like syndrome known as dengue fever [DF] to the most severe forms of the disease, which are characterized by coagulopathy, increased vascular permeability, and plasma leakage dengue hemorrhagic fever [DHF] which eventually leads to dengue shock syndrome DS [ 5 ]. Further, this attempt warrants exploring the bioactive compounds and possible mechanisms of action and will pave the way to develop a new antidengue drug lead from E.
The rich cultural heritage of the Philippines is a rich resource of indigenous health knowledge. Introduction Edngue is a viral disease that impose the greatest human and economic burden in tropical and subtropical regions [ 1 ]. There are limited ethnobotanical studies conducted in Luzon, the largest island in the Philippines. Effect of Hippophae rhamnoides leaf extracts against Dengue virus infection in human suphorbia macrophages.
Mosquito bites are the only route of DENV spread. Within this period, 17 and 15 cases of dengue were reported in the municipalities of Balungao and San Fabian i. The locals speak Bolinao, a minority dialect, and Ilocano and thrives on farming and deep sea fishing.
Plants as source of drugs. The CC 50 of ethanol extract of F. Perspect Plant Ecol Evol Syst. Green Countries or areas at risk of dengue, Herbarium specimens and photographs of the plants in their natural habitats were submitted to the Philippine National Herbarium euphorboa authentication.
The use of herbs, however, is not a new phenomenon. A possible strategy in hirrta treatment ddngue dengue is to use chimeric tetravalent vaccines that show high neutralizing antibody against all dengue serotypes [ 915 ]. A high FL is reflected when E. Herbal medicine has been euphotbia popular with the advent of naturopathy. Tally of use reports of E. Natural products have become the main source of test material in the development of antiviral drugs based on traditional medical practices [ 50 ].
Journal of Tropical Medicine
Cost-effectiveness is still being monitored. Bock G, Goode J eds New treatment strategies for dengue and other flaviviral diseases. However, the mechanism of action is still unknown and the antiviral properties and its ability to increase blood platelets are currently euphorbis.
Overview of studies on plant species used as anti-dengue The use of herbal-based medicine and medicinal plants to treat many diseases is growing worldwide as they has few or no adverse effects. It is used widely as traditional medicine by native people of the Peruvian rainforest [ 68 ]. Dengue fever treatment with Carica papaya leaves extracts. Sincere thanks are due to Dr.
Previously, the antiviral, antibacterial, antimalarial, antifungal, anti-inflammatory, anthelmintic, and antitumor properties of the debgue have been validated [ 16 ]. Further euphoebia of ethyl acetate fraction revealed the presence of 9 compounds. Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue.
Psidium guajava Psidium guajava belongs to family Myrtaceae. View at Google Scholar K. This is an open access article distributed under the Creative Euphorbbia Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.