Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and. Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. Eur J Haematol Suppl. Mar;(71) doi: /j x. Immune thrombocytopenic purpura: epidemiology and implications for.

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The authors declare no conflict of interest or commercial affiliation related to this study. Initial treatment usually consists of the administration of corticosteroidsa group of medications that suppress the immune system. This increased risk of death with ITP is largely concentrated in the middle-aged and elderly. Other immunosuppresants, which are steroid sparing drugs like mycophenolate mofetil and azathioprine, are becoming more popular for their effectiveness. An ITP patient with an extremely low count is vulnerable to internal bleeding caused by blunt abdominal traumaas might be experienced in a motor vehicle crash.

Romiplostim or standard of care in patients with immune thrombocytopenia. It causes a characteristic purpuric rash and an increased tendency to bleed. The bleeding manifestations of thrombocytopenia are described as mucocutaneous to distinguish them from coagulation disorders like hemophilia. Children should be discouraged from rough contact sports or other activities that increase the risk of trauma. However, the use of bleeding time in diagnosis is discouraged by the American Society of Hematology practice guidelines [10] and a normal bleeding time does not exclude a platelet disorder.


Abstract Idiopathic thrombocytopenic purpura ITP is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. Some profess that H.

Immune thrombocytopenic purpura – Wikipedia

Past medical history revealed that patient was known case of epilepsy since 7 years of age and was on tablet eptoin, tablet carbamazepine for purpuura 12 years.

The first case of association of H.

Journal List Gastroenterology Res v. Other biochemical examinations, liver function tests, and ultrasonography of abdomen were normal. Not to be confused with autoimmune thrombotic thrombocytopenic purpura.

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In adults, particularly those living in areas with a high prevalence of Helicobacter pylori which normally inhabits the stomach wall and has been associated tromboeitopenia peptic ulcersidentification and treatment of this infection has been shown to improve platelet counts in a third of patients. We report a case of year-old woman with ITP who experienced a complete and lasting normalization of the platelet count after receiving treatment for the eradication of H.

In conclusion, eradication of H.


Bleeding time is usually prolonged. A report of 66 cases. Such secondary causes include leukemiamedications e. Foreign Hemolytic disease of the newborn. The idiopathic thrombocytopenic purpura ITPfirst described by P. The mechanism of action of anti-D is not fully understood.

Ninety-six percent trombositopeniw reported ITP-related deaths were individuals 45 years or older. Support Center Support Center. Dapsone for chronic autoimmune thrombocytopenic purpura: Initial clinical trials show it to be effective in chronic ITP. Later withdrawal of wysolone resulted in the relapse steroid dependant thrombocytopenia of another episode of melena. Some children may need treatment.

Immune thrombocytopenic purpura

First, it has to be determined that there are no blood abnormalities other than a low platelet count, and no physical signs other than bleeding. Patient started treatment 7 years back and was on tablet isosorbide dinitrate 10 mg, tablet atenelol 25 mg, tablet envas 5 mg and patient had discontinued aspirin 6 months back. N Engl J Med ; Chronic idiopathic thrombocytopenic purpura.

Idiopathic thrombocytopenic purpura ITP is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause.

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