INFeD® improved the hemoglobin response to erythropoietic therapy in patients with documented INFeD® full Prescribing Information. Watson Pharma, Inc. 1 mL of INFeD provides 50 mg of elemental iron UpToDate (courtesy of Lexicomp), or the prescribing information. INFeD: INFeD is administered by intramuscular or intravenous injection. Before . during the acute phase of infectious renal disease (manufacturer’s information) . Therefore, the therapeutic prescription use of iron is usually compatible with.

Author: Nibar Tojazshura
Country: Central African Republic
Language: English (Spanish)
Genre: Science
Published (Last): 23 November 2008
Pages: 108
PDF File Size: 20.88 Mb
ePub File Size: 11.72 Mb
ISBN: 855-6-55188-333-1
Downloads: 56791
Price: Free* [*Free Regsitration Required]
Uploader: Akigore

While iron is excreted into breast-milk, the iron content of breast milk is not readily affected by the iron content of the maternal diet or the maternal serum iron level. Ferric iron is then gradually released into the plasma where it combines rapidly with transferrin.

PDR Search

In the study of infants with the gestational age of about 28 weeks, a dose of 0. If test dose uneventful, give the remainder of the total dose as 50 mg of prescribiing dextran per day IM or slow IV until the total calculated dose is given.

Do not administer iron dextran to infrd with evidence of iron overload e. According to the manufacturer, caution should be exercised if iron dextran is administered to a nursing mother.

INFeD (iron dextran) dose, indications, adverse effects, interactions from

Subcutaneous injection of iron dextran results in slow absorption and staining of subcutaneous tissue. A therapeutic response to treatment with iron iinformation is dependent on the patient’s ability to absorb and use the iron, and it is influenced by the cause of the deficiency as well as other illnesses that can affect normal erythropoiesis. Minor It is important that iron stores be replete before beginning therapy with darbepoetin alfa due to increased iron utilization.


Some patients received epoetin in conjunction with parenteral iron. Iron dextran is classified in FDA pregnancy risk category C. Uptake by these cells occurs at a rate of about 10—20 mg per hour.

A test dose should be administered before the informtion of the therapeutic dose. Major In general, oral mineral supplements should not be given since they may block the oral absorption of trientine.

In general, prescribnig supplementation should not begin in premature infants until adequate vitamin E is supplied in the diet; human breast milk and modern infant formulas usually supply adequate dietary vitamin E.

Iron dextran (INFeD) | – A Hematology Oncology Wiki

Observe patient for at least 1 hour after test dose administration. If the patient is standing, inject iron dextran into the buttock opposite the weight-bearing leg. Iron dextran should rpescribing administered to pregnant women only if the benefits outweigh the potential risks to the fetus. The following are generally accepted limits in the treatment of iron-deficient patients.

Iron dextran is contraindicated in patients with iron dextran hypersensitivity. In general, do not administer parenteral iron concomitantly with other iron preparations e. However, iron deficiency may develop, especially in children and menstruating or pregnant women, or as a result of the low copper diet recommended for Wilson’s prescribingg.


Give INFeD test doses gradually over at least 30 seconds. Since deferiprone has the potential to bind polyvalent cations e. Inject deeply into the upper outer quadrant of the buttock gluteus maximus only using a 2- or 3-inch, or gauge needle.

There is some concern that intravenously administered iron is not used appropriately by the body. Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition.

Facilities for cardiopulmonary resuscitation and personnel trained in the detection and treatment of anaphylactoid reactions must be available during administration. Infants and Children 4 months and older weighing 5 to 9. The extent of risk for anaphylactoid reactions to any specific iron dextran product is unknown and may vary among products. Adult men, Adolescent males, and Postmenopausal women.

Iron dextran (INFeD)

Intermittent hemodialysis Before supplementing hemodialysis patients with iron dextran, a diagnosis of absolute or functional iron deficiency should be made. A value of The chelate is excreted in the urine and in the feces via bile. Slow intermittent intravenous IV injection:

Author: admin