LEI 11418 PDF

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The data indicated that GBE repressed glucose uptake under normal conditions, while it dramatically improved glucose tolerance under insulin-resistant conditions. Abstract Our aim is to investigate the potential therapeutic value of morin against leei and elucidate the mechanism of action.

Gene Ontology GO Terms.

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We investigated the effects of GBE on glucose consumption, glucokinase activity, and mRNA levels of key genes ,ei glucose metabolism and the insulin signaling pathway. How does Europe PMC derive its citations network? Europe PMC requires Javascript to function effectively.

It is said that GBE treatment could avoid drug-induced obesity. To better show its efficacy, we included a control group that was treated with rosiglitazone, a type of thiazolidinedione TZD. How does Europe PMC derive its citations network? Find all citations in this journal default.

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Journal of Natural Medicines [24 Jul72 4: Morin treatment also increased the number of trabecular bones in DEX-induced rats. Pathological examination was performed by hematoxylin and eosin staining. Read Article at publisher’s site. Our data suggest that GBE has the potential to prevent insulin ,ei and is a promising anti-diabetic drug.

Either your web browser doesn’t support Javascript or it is currently turned off. Abstract Ginkgo biloba, an herbal medication, is capable of lowering glucose, fat, and lipid peroxide in diabetic patients. Or filter your current search. Body weight and BMD were both significantly decreased in osteoporotic rats, although BMD was partially restored by intraperitoneal morin administration.

In the latter case, please turn on Javascript support in your web browser and reload this page. Body weight was regularly monitored.

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Here, we uncovered the therapeutic effect of morin against osteoporosis and demonstrated its suppressive action on the MAPK pathway in this disease. Journal of Natural Medicines [03 Sep65 1: The relative expression of osteogenic and bone resorption markers was determined by real-time polymerase chain reaction and Western blotting, respectively. Body mineral density BMD was determined at proximal femurs using dual energy X-ray absorptiometry.

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Gene Ontology GO Terms. Mechanistically, morin reversed the decrease of osteogenic markers and increase of bone resorption markers, which might eventually be mediated by modulation of MAPK signaling cascades.

No matching affiliation detected. CitePeer Related Articles http: In the current study, we tested the hypothesis that Ginkgo biloba extract GBE prevented hyperinsulinism-induced glucose intolerance in hepatocytes.

It should be noted that, unlike rosiglitazone, GBE did not stimulate excessive glucose uptake as it improved glucose tolerance. Find all citations in this journal default. Europe PMC requires Javascript to function effectively.

Furthermore, after analyzing gene expression, we suggest that GBE chiefly exerts its effects by stimulating IRS-2 transcription.

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Or filter your current search. CitePeer Related Articles http: In the latter case, please turn on Javascript support in your web browser and reload this page. Read Article at publisher’s site.

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